Neuroregeneration (NR) is a long-sought medical dream which has intrigued vast research in the past decades. A traditional physiologic dogma that central nervous system does not regenerate has been strongly challenged in the recent years since the advent of the stem cell era. Stem cell research in the regenerative field passes through three main stages. The first stage is the in-vitro experiments which studies the exact molecular and cellular mechanisms underlying stem cell-mediated NR. The second stage is the application of these data in experimental animal settings to provide "proof of concept" of stem cell therapy in animal models. The final step is the translation of these data in pilot clinical trials. In this review, we will try to gather the different data of stem cell-mediated NR from various experimental and clinical researches.
| Published in |
American Journal of Bioscience and Bioengineering (Volume 3, Issue 4-1)
This article belongs to the Special Issue Stem Cells for Neuro-Regeneration: Where Do We Stand |
| DOI | 10.11648/j.bio.s.2015030401.19 |
| Page(s) | 56-70 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2015. Published by Science Publishing Group |
Neuroregeneration, Stem Cells, Mesenchymal Stem Cells, Parkinsonism, Transdiffereniation
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APA Style
Wagih A., Elhawary S., Ellessy R. M., Esam B., Tarek I., et al. (2015). Stem Cells for Neuro-regeneration: State of the Art. American Journal of Bioscience and Bioengineering, 3(4-1), 56-70. https://doi.org/10.11648/j.bio.s.2015030401.19
ACS Style
Wagih A.; Elhawary S.; Ellessy R. M.; Esam B.; Tarek I., et al. Stem Cells for Neuro-regeneration: State of the Art. Am. J. BioSci. Bioeng. 2015, 3(4-1), 56-70. doi: 10.11648/j.bio.s.2015030401.19
AMA Style
Wagih A., Elhawary S., Ellessy R. M., Esam B., Tarek I., et al. Stem Cells for Neuro-regeneration: State of the Art. Am J BioSci Bioeng. 2015;3(4-1):56-70. doi: 10.11648/j.bio.s.2015030401.19
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Download@article{10.11648/j.bio.s.2015030401.19,
author = {Wagih A. and Elhawary S. and Ellessy R. M. and Esam B. and Tarek I. and Aamer M.},
title = {Stem Cells for Neuro-regeneration: State of the Art},
journal = {American Journal of Bioscience and Bioengineering},
volume = {3},
number = {4-1},
pages = {56-70},
doi = {10.11648/j.bio.s.2015030401.19},
url = {https://doi.org/10.11648/j.bio.s.2015030401.19},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.bio.s.2015030401.19},
abstract = {Neuroregeneration (NR) is a long-sought medical dream which has intrigued vast research in the past decades. A traditional physiologic dogma that central nervous system does not regenerate has been strongly challenged in the recent years since the advent of the stem cell era. Stem cell research in the regenerative field passes through three main stages. The first stage is the in-vitro experiments which studies the exact molecular and cellular mechanisms underlying stem cell-mediated NR. The second stage is the application of these data in experimental animal settings to provide "proof of concept" of stem cell therapy in animal models. The final step is the translation of these data in pilot clinical trials. In this review, we will try to gather the different data of stem cell-mediated NR from various experimental and clinical researches.},
year = {2015}
}
TY - JOUR T1 - Stem Cells for Neuro-regeneration: State of the Art AU - Wagih A. AU - Elhawary S. AU - Ellessy R. M. AU - Esam B. AU - Tarek I. AU - Aamer M. Y1 - 2015/07/09 PY - 2015 N1 - https://doi.org/10.11648/j.bio.s.2015030401.19 DO - 10.11648/j.bio.s.2015030401.19 T2 - American Journal of Bioscience and Bioengineering JF - American Journal of Bioscience and Bioengineering JO - American Journal of Bioscience and Bioengineering SP - 56 EP - 70 PB - Science Publishing Group SN - 2328-5893 UR - https://doi.org/10.11648/j.bio.s.2015030401.19 AB - Neuroregeneration (NR) is a long-sought medical dream which has intrigued vast research in the past decades. A traditional physiologic dogma that central nervous system does not regenerate has been strongly challenged in the recent years since the advent of the stem cell era. Stem cell research in the regenerative field passes through three main stages. The first stage is the in-vitro experiments which studies the exact molecular and cellular mechanisms underlying stem cell-mediated NR. The second stage is the application of these data in experimental animal settings to provide "proof of concept" of stem cell therapy in animal models. The final step is the translation of these data in pilot clinical trials. In this review, we will try to gather the different data of stem cell-mediated NR from various experimental and clinical researches. VL - 3 IS - 4-1 ER -
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