Systemic lupus erythematosus is an autoimmune Inflammatory disease that can affect multiple systems and organs of the body including skin, kidneys, lungs, joints and nervous system.Some previous studies up light thatSLE was associated with increased risk of Acute leukemia (SIR = 2.3). The incidence ofthe association of AMLand SLE is not known but there are few case reports in literature. The aim of this report was to up light the difficulties wich occurred in the diagnosis and the management of acute myeloid leukemia in patient with systemic lupus erythematosus. Patient, 43 years old, diabetic treat withinsulin, wichsister is followed for Behcet's disease, was admited for AML with trisomy of chromosome 4 and 8 and thrombophlebitis of the superior sagittal sinus, Chest CT-Scan showed minimal bilateral pleural effusion. She was treated according to Morocco National protocol AML-MA-2011. CT-Scan was done atday 12 ofchemotherapy and noticedthe persistance of the minimal bilateral pleural effusion.At day 19 the patient presentedmalar rash, and right axillary adenitis. The biopsy of the adenitis show the presence of LE cells. According to internal physician recommendations we add steroids to the treatement. The cough and fever deasapear. The CT-scan for control was normal after two weeks of steroids. Patient is in complete remission after induction I. After a following-up of five months, the patient still well,but present severy infections during chemotherapy cycles and a bad tolerance for the treatement. The association SLE-AML is rare. The diagnosis of the association SLE-AML is difficult. It is management is also difficult according to commorbidity, severy infectious because of dicline of immunity, and less tolerance to AML chemotherapy.
| Published in | American Journal of Internal Medicine (Volume 6, Issue 1) |
| DOI | 10.11648/j.ajim.20180601.14 |
| Page(s) | 25-28 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2018. Published by Science Publishing Group |
Acute Myeloid Leukemia, Systemic Lupus Erythematosus, Association
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APA Style
Romaric Mahutondji Massi, Mouna Lamchahab, Marième Camara, Bienvenu Houssou, Bouchra Oukkache, et al. (2018). Association of Acute Myeloid Leukemia and Systemic Lupus Erythematosus: A Case Report. American Journal of Internal Medicine, 6(1), 25-28. https://doi.org/10.11648/j.ajim.20180601.14
ACS Style
Romaric Mahutondji Massi; Mouna Lamchahab; Marième Camara; Bienvenu Houssou; Bouchra Oukkache, et al. Association of Acute Myeloid Leukemia and Systemic Lupus Erythematosus: A Case Report. Am. J. Intern. Med. 2018, 6(1), 25-28. doi: 10.11648/j.ajim.20180601.14
AMA Style
Romaric Mahutondji Massi, Mouna Lamchahab, Marième Camara, Bienvenu Houssou, Bouchra Oukkache, et al. Association of Acute Myeloid Leukemia and Systemic Lupus Erythematosus: A Case Report. Am J Intern Med. 2018;6(1):25-28. doi: 10.11648/j.ajim.20180601.14
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Download@article{10.11648/j.ajim.20180601.14,
author = {Romaric Mahutondji Massi and Mouna Lamchahab and Marième Camara and Bienvenu Houssou and Bouchra Oukkache and Asmaa Quessar},
title = {Association of Acute Myeloid Leukemia and Systemic Lupus Erythematosus: A Case Report},
journal = {American Journal of Internal Medicine},
volume = {6},
number = {1},
pages = {25-28},
doi = {10.11648/j.ajim.20180601.14},
url = {https://doi.org/10.11648/j.ajim.20180601.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20180601.14},
abstract = {Systemic lupus erythematosus is an autoimmune Inflammatory disease that can affect multiple systems and organs of the body including skin, kidneys, lungs, joints and nervous system.Some previous studies up light thatSLE was associated with increased risk of Acute leukemia (SIR = 2.3). The incidence ofthe association of AMLand SLE is not known but there are few case reports in literature. The aim of this report was to up light the difficulties wich occurred in the diagnosis and the management of acute myeloid leukemia in patient with systemic lupus erythematosus. Patient, 43 years old, diabetic treat withinsulin, wichsister is followed for Behcet's disease, was admited for AML with trisomy of chromosome 4 and 8 and thrombophlebitis of the superior sagittal sinus, Chest CT-Scan showed minimal bilateral pleural effusion. She was treated according to Morocco National protocol AML-MA-2011. CT-Scan was done atday 12 ofchemotherapy and noticedthe persistance of the minimal bilateral pleural effusion.At day 19 the patient presentedmalar rash, and right axillary adenitis. The biopsy of the adenitis show the presence of LE cells. According to internal physician recommendations we add steroids to the treatement. The cough and fever deasapear. The CT-scan for control was normal after two weeks of steroids. Patient is in complete remission after induction I. After a following-up of five months, the patient still well,but present severy infections during chemotherapy cycles and a bad tolerance for the treatement. The association SLE-AML is rare. The diagnosis of the association SLE-AML is difficult. It is management is also difficult according to commorbidity, severy infectious because of dicline of immunity, and less tolerance to AML chemotherapy.},
year = {2018}
}
TY - JOUR T1 - Association of Acute Myeloid Leukemia and Systemic Lupus Erythematosus: A Case Report AU - Romaric Mahutondji Massi AU - Mouna Lamchahab AU - Marième Camara AU - Bienvenu Houssou AU - Bouchra Oukkache AU - Asmaa Quessar Y1 - 2018/04/08 PY - 2018 N1 - https://doi.org/10.11648/j.ajim.20180601.14 DO - 10.11648/j.ajim.20180601.14 T2 - American Journal of Internal Medicine JF - American Journal of Internal Medicine JO - American Journal of Internal Medicine SP - 25 EP - 28 PB - Science Publishing Group SN - 2330-4324 UR - https://doi.org/10.11648/j.ajim.20180601.14 AB - Systemic lupus erythematosus is an autoimmune Inflammatory disease that can affect multiple systems and organs of the body including skin, kidneys, lungs, joints and nervous system.Some previous studies up light thatSLE was associated with increased risk of Acute leukemia (SIR = 2.3). The incidence ofthe association of AMLand SLE is not known but there are few case reports in literature. The aim of this report was to up light the difficulties wich occurred in the diagnosis and the management of acute myeloid leukemia in patient with systemic lupus erythematosus. Patient, 43 years old, diabetic treat withinsulin, wichsister is followed for Behcet's disease, was admited for AML with trisomy of chromosome 4 and 8 and thrombophlebitis of the superior sagittal sinus, Chest CT-Scan showed minimal bilateral pleural effusion. She was treated according to Morocco National protocol AML-MA-2011. CT-Scan was done atday 12 ofchemotherapy and noticedthe persistance of the minimal bilateral pleural effusion.At day 19 the patient presentedmalar rash, and right axillary adenitis. The biopsy of the adenitis show the presence of LE cells. According to internal physician recommendations we add steroids to the treatement. The cough and fever deasapear. The CT-scan for control was normal after two weeks of steroids. Patient is in complete remission after induction I. After a following-up of five months, the patient still well,but present severy infections during chemotherapy cycles and a bad tolerance for the treatement. The association SLE-AML is rare. The diagnosis of the association SLE-AML is difficult. It is management is also difficult according to commorbidity, severy infectious because of dicline of immunity, and less tolerance to AML chemotherapy. VL - 6 IS - 1 ER -
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