Constitutional Pericentric Inversion of Chromosome 9 and Chronic Myeloid Leukemia

Salil Vaniawala; Gadhia Pankaj

doi:doi:10.11648/j.ajcem.20140206.13

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Constitutional Pericentric Inversion of Chromosome 9 and Chronic Myeloid Leukemia

Salil Vaniawala, Gadhia Pankaj

Published in American Journal of Clinical and Experimental Medicine (Volume 2, Issue 6)

Received: 10 October 2014 Accepted: 6 November 2014 Published: 20 November 2014

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Abstract

In the present study, we screened the bone marrow chromosome database entries between March, 2004 and December, 2013 to identify cases with inv(9) along with t(9;22) variations. Our study recorded 2300 cases of confirmed CML (Ph positive), of which only 12 (0.52%) cases had inv(9) and t(9;22). The association between inv(9) and t(9;22) is not fully explored. Therefore more number of cases is required to shed light on its important role, if any, especially in bone-marrow transplantation and drug resistance.

Published in	American Journal of Clinical and Experimental Medicine (Volume 2, Issue 6)
DOI	10.11648/j.ajcem.20140206.13
Page(s)	128-131
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2014. Published by Science Publishing Group

Keywords

Pericentric Inv (9), CML, t(9; 22), Bone-Marrow

References

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[7]	M. A. Seabright. “A rapid banding technique for human chromosome”. Lancet. Vol. 2,pp. 971-972, 1971
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[9]	S.G.Lee, T.S.Park, G. Lim, K.A.Lee, J. Song and J.R.Choi. “Constitutional pericentric inversion and hematological disorders. A Korean tertiary Institution experience over eight years. Vol.40, pp.273-277, 2010.
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[12]	T. S. Wan, S.K. Ma, and I.C.Chan. “Acquired pericentric inversion of chromosome 9 in essential thrombocytopenia”. Humn. Genet. Vol. 106, pp.669-670, 2000.
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[14]	B. Suh, J. Song, J. Kim, T.S. Park and J. R. Choi. “Constitutional pericentric inversion 9 in Korean patients with chronic myelo- genous leukemia”. Kor.J. Lab. Med. Vol.30, pp. 218-223, 2010.

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APA Style

Salil Vaniawala, Gadhia Pankaj. (2014). Constitutional Pericentric Inversion of Chromosome 9 and Chronic Myeloid Leukemia. American Journal of Clinical and Experimental Medicine, 2(6), 128-131. https://doi.org/10.11648/j.ajcem.20140206.13

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ACS Style

Salil Vaniawala; Gadhia Pankaj. Constitutional Pericentric Inversion of Chromosome 9 and Chronic Myeloid Leukemia. Am. J. Clin. Exp. Med. 2014, 2(6), 128-131. doi: 10.11648/j.ajcem.20140206.13

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AMA Style

Salil Vaniawala, Gadhia Pankaj. Constitutional Pericentric Inversion of Chromosome 9 and Chronic Myeloid Leukemia. Am J Clin Exp Med. 2014;2(6):128-131. doi: 10.11648/j.ajcem.20140206.13

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@article{10.11648/j.ajcem.20140206.13,
  author = {Salil Vaniawala and Gadhia Pankaj},
  title = {Constitutional Pericentric Inversion of Chromosome 9 and Chronic Myeloid Leukemia},
  journal = {American Journal of Clinical and Experimental Medicine},
  volume = {2},
  number = {6},
  pages = {128-131},
  doi = {10.11648/j.ajcem.20140206.13},
  url = {https://doi.org/10.11648/j.ajcem.20140206.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcem.20140206.13},
  abstract = {In the present study, we screened the bone marrow chromosome database entries between March, 2004 and December, 2013 to identify cases with inv(9) along with t(9;22) variations. Our study recorded 2300 cases of confirmed CML (Ph positive), of which only 12 (0.52%) cases had inv(9) and t(9;22). The association between inv(9) and t(9;22) is not fully explored. Therefore more number of cases is required to shed light on its important role, if any, especially in bone-marrow transplantation and drug resistance.},
 year = {2014}
}

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TY  - JOUR
T1  - Constitutional Pericentric Inversion of Chromosome 9 and Chronic Myeloid Leukemia
AU  - Salil Vaniawala
AU  - Gadhia Pankaj
Y1  - 2014/11/20
PY  - 2014
N1  - https://doi.org/10.11648/j.ajcem.20140206.13
DO  - 10.11648/j.ajcem.20140206.13
T2  - American Journal of Clinical and Experimental Medicine
JF  - American Journal of Clinical and Experimental Medicine
JO  - American Journal of Clinical and Experimental Medicine
SP  - 128
EP  - 131
PB  - Science Publishing Group
SN  - 2330-8133
UR  - https://doi.org/10.11648/j.ajcem.20140206.13
AB  - In the present study, we screened the bone marrow chromosome database entries between March, 2004 and December, 2013 to identify cases with inv(9) along with t(9;22) variations. Our study recorded 2300 cases of confirmed CML (Ph positive), of which only 12 (0.52%) cases had inv(9) and t(9;22). The association between inv(9) and t(9;22) is not fully explored. Therefore more number of cases is required to shed light on its important role, if any, especially in bone-marrow transplantation and drug resistance.
VL  - 2
IS  - 6
ER  -

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Author Information

Salil Vaniawala

Molecular Cytogenetic Unit, S. N. Gene Laboratory and Research Centre, President Plaza-A , Near RTO circle, Surat-395001, India
Gadhia Pankaj

P. K. Gadhia, Molecular Cytogenetic Unit, S. N. Gene Lab. and Research Centre, Near RTO circle, Surat – 395001. India

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APA Style

Salil Vaniawala, Gadhia Pankaj. (2014). Constitutional Pericentric Inversion of Chromosome 9 and Chronic Myeloid Leukemia. American Journal of Clinical and Experimental Medicine, 2(6), 128-131. https://doi.org/10.11648/j.ajcem.20140206.13

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ACS Style

Salil Vaniawala; Gadhia Pankaj. Constitutional Pericentric Inversion of Chromosome 9 and Chronic Myeloid Leukemia. Am. J. Clin. Exp. Med. 2014, 2(6), 128-131. doi: 10.11648/j.ajcem.20140206.13

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AMA Style

Salil Vaniawala, Gadhia Pankaj. Constitutional Pericentric Inversion of Chromosome 9 and Chronic Myeloid Leukemia. Am J Clin Exp Med. 2014;2(6):128-131. doi: 10.11648/j.ajcem.20140206.13

Copy | Download

@article{10.11648/j.ajcem.20140206.13,
  author = {Salil Vaniawala and Gadhia Pankaj},
  title = {Constitutional Pericentric Inversion of Chromosome 9 and Chronic Myeloid Leukemia},
  journal = {American Journal of Clinical and Experimental Medicine},
  volume = {2},
  number = {6},
  pages = {128-131},
  doi = {10.11648/j.ajcem.20140206.13},
  url = {https://doi.org/10.11648/j.ajcem.20140206.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcem.20140206.13},
  abstract = {In the present study, we screened the bone marrow chromosome database entries between March, 2004 and December, 2013 to identify cases with inv(9) along with t(9;22) variations. Our study recorded 2300 cases of confirmed CML (Ph positive), of which only 12 (0.52%) cases had inv(9) and t(9;22). The association between inv(9) and t(9;22) is not fully explored. Therefore more number of cases is required to shed light on its important role, if any, especially in bone-marrow transplantation and drug resistance.},
 year = {2014}
}

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TY  - JOUR
T1  - Constitutional Pericentric Inversion of Chromosome 9 and Chronic Myeloid Leukemia
AU  - Salil Vaniawala
AU  - Gadhia Pankaj
Y1  - 2014/11/20
PY  - 2014
N1  - https://doi.org/10.11648/j.ajcem.20140206.13
DO  - 10.11648/j.ajcem.20140206.13
T2  - American Journal of Clinical and Experimental Medicine
JF  - American Journal of Clinical and Experimental Medicine
JO  - American Journal of Clinical and Experimental Medicine
SP  - 128
EP  - 131
PB  - Science Publishing Group
SN  - 2330-8133
UR  - https://doi.org/10.11648/j.ajcem.20140206.13
AB  - In the present study, we screened the bone marrow chromosome database entries between March, 2004 and December, 2013 to identify cases with inv(9) along with t(9;22) variations. Our study recorded 2300 cases of confirmed CML (Ph positive), of which only 12 (0.52%) cases had inv(9) and t(9;22). The association between inv(9) and t(9;22) is not fully explored. Therefore more number of cases is required to shed light on its important role, if any, especially in bone-marrow transplantation and drug resistance.
VL  - 2
IS  - 6
ER  -

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