Synthesis, Magnetic, Spectral and Biological Studies of Copper(II) Complexes of 4-Benzoyl-3-Methyl-1-Phenyl-2-Pyrazolin-5-One N(4)-Substituted Thiosemicarbazones

Ayman K. El-Sawaf; Amal Abdel Fatah Nassar; El-Sayed El-Samanody

doi:doi:10.11648/j.sjc.20140203.12

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Synthesis, Magnetic, Spectral and Biological Studies of Copper(II) Complexes of 4-Benzoyl-3-Methyl-1-Phenyl-2-Pyrazolin-5-One N(4)-Substituted Thiosemicarbazones

Ayman K. El-Sawaf, Amal Abdel Fatah Nassar, El-Sayed El-Samanody

Published in Science Journal of Chemistry (Volume 2, Issue 3)

Received: 11 August 2014 Accepted: 18 August 2014 Published: 30 August 2014

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Abstract

The synthesis and characterization of copper(II) complexes with 4-benzoyl-3-methyl-1-phenyl-2-pyrazolin-5-one thiosemicarbazone and N(4)-substituted thiosemicarbazones are reported. Elemental analysis, molar conductivities, magnetic measurements and spectral (i.r., electronic, e.s.r., and n.m.r.) studies have been used to characterize the complexes. The i.r. spectra show that the thiosemicarbazones behave as bidentate ligands, either in the thione or thiolato form. Stereochemistries are proposed for the complexes on the basis of spectral and magnetic studies. Both the thiosemicarbazones and their complexes show either modest or no growth inhibitory activity against Aspergillus niger and Paecilomyces variotii.

Published in	Science Journal of Chemistry (Volume 2, Issue 3)
DOI	10.11648/j.sjc.20140203.12
Page(s)	17-26
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2014. Published by Science Publishing Group

Keywords

Synthesis, Thiosemicarbazones, Characterization, Complexes, Stereochemistries, Antifungal

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APA Style

Ayman K. El-Sawaf, Amal Abdel Fatah Nassar, El-Sayed El-Samanody. (2014). Synthesis, Magnetic, Spectral and Biological Studies of Copper(II) Complexes of 4-Benzoyl-3-Methyl-1-Phenyl-2-Pyrazolin-5-One N(4)-Substituted Thiosemicarbazones. Science Journal of Chemistry, 2(3), 17-26. https://doi.org/10.11648/j.sjc.20140203.12

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ACS Style

Ayman K. El-Sawaf; Amal Abdel Fatah Nassar; El-Sayed El-Samanody. Synthesis, Magnetic, Spectral and Biological Studies of Copper(II) Complexes of 4-Benzoyl-3-Methyl-1-Phenyl-2-Pyrazolin-5-One N(4)-Substituted Thiosemicarbazones. Sci. J. Chem. 2014, 2(3), 17-26. doi: 10.11648/j.sjc.20140203.12

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AMA Style

Ayman K. El-Sawaf, Amal Abdel Fatah Nassar, El-Sayed El-Samanody. Synthesis, Magnetic, Spectral and Biological Studies of Copper(II) Complexes of 4-Benzoyl-3-Methyl-1-Phenyl-2-Pyrazolin-5-One N(4)-Substituted Thiosemicarbazones. Sci J Chem. 2014;2(3):17-26. doi: 10.11648/j.sjc.20140203.12

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@article{10.11648/j.sjc.20140203.12,
  author = {Ayman K. El-Sawaf and Amal Abdel Fatah Nassar and El-Sayed El-Samanody},
  title = {Synthesis, Magnetic, Spectral and Biological Studies of Copper(II) Complexes of 4-Benzoyl-3-Methyl-1-Phenyl-2-Pyrazolin-5-One N(4)-Substituted Thiosemicarbazones},
  journal = {Science Journal of Chemistry},
  volume = {2},
  number = {3},
  pages = {17-26},
  doi = {10.11648/j.sjc.20140203.12},
  url = {https://doi.org/10.11648/j.sjc.20140203.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjc.20140203.12},
  abstract = {The synthesis and characterization of copper(II) complexes with 4-benzoyl-3-methyl-1-phenyl-2-pyrazolin-5-one thiosemicarbazone and N(4)-substituted thiosemicarbazones are reported. Elemental analysis, molar conductivities, magnetic measurements and spectral (i.r., electronic, e.s.r., and n.m.r.) studies have been used to characterize the complexes. The i.r. spectra show that the thiosemicarbazones behave as bidentate ligands, either in the thione or thiolato form. Stereochemistries are proposed for the complexes on the basis of spectral and magnetic studies. Both the thiosemicarbazones and their complexes show either modest or no growth inhibitory activity against Aspergillus niger and Paecilomyces variotii.},
 year = {2014}
}

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TY  - JOUR
T1  - Synthesis, Magnetic, Spectral and Biological Studies of Copper(II) Complexes of 4-Benzoyl-3-Methyl-1-Phenyl-2-Pyrazolin-5-One N(4)-Substituted Thiosemicarbazones
AU  - Ayman K. El-Sawaf
AU  - Amal Abdel Fatah Nassar
AU  - El-Sayed El-Samanody
Y1  - 2014/08/30
PY  - 2014
N1  - https://doi.org/10.11648/j.sjc.20140203.12
DO  - 10.11648/j.sjc.20140203.12
T2  - Science Journal of Chemistry
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JO  - Science Journal of Chemistry
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PB  - Science Publishing Group
SN  - 2330-099X
UR  - https://doi.org/10.11648/j.sjc.20140203.12
AB  - The synthesis and characterization of copper(II) complexes with 4-benzoyl-3-methyl-1-phenyl-2-pyrazolin-5-one thiosemicarbazone and N(4)-substituted thiosemicarbazones are reported. Elemental analysis, molar conductivities, magnetic measurements and spectral (i.r., electronic, e.s.r., and n.m.r.) studies have been used to characterize the complexes. The i.r. spectra show that the thiosemicarbazones behave as bidentate ligands, either in the thione or thiolato form. Stereochemistries are proposed for the complexes on the basis of spectral and magnetic studies. Both the thiosemicarbazones and their complexes show either modest or no growth inhibitory activity against Aspergillus niger and Paecilomyces variotii.
VL  - 2
IS  - 3
ER  -

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Author Information

Ayman K. El-Sawaf

Chemistry Department, College of Science and Humanity Studies, Salman bin Abdulaziz University, AlKharj, KSA.11942
Amal Abdel Fatah Nassar

Chemistry Department, College of Education for Girls, Salman bin Abdulaziz University, KSA
El-Sayed El-Samanody

Chemistry Department, College of Science and Humanity Studies, Salman bin Abdulaziz University, AlKharj, KSA.11942

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APA Style

Ayman K. El-Sawaf, Amal Abdel Fatah Nassar, El-Sayed El-Samanody. (2014). Synthesis, Magnetic, Spectral and Biological Studies of Copper(II) Complexes of 4-Benzoyl-3-Methyl-1-Phenyl-2-Pyrazolin-5-One N(4)-Substituted Thiosemicarbazones. Science Journal of Chemistry, 2(3), 17-26. https://doi.org/10.11648/j.sjc.20140203.12

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ACS Style

Ayman K. El-Sawaf; Amal Abdel Fatah Nassar; El-Sayed El-Samanody. Synthesis, Magnetic, Spectral and Biological Studies of Copper(II) Complexes of 4-Benzoyl-3-Methyl-1-Phenyl-2-Pyrazolin-5-One N(4)-Substituted Thiosemicarbazones. Sci. J. Chem. 2014, 2(3), 17-26. doi: 10.11648/j.sjc.20140203.12

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AMA Style

Ayman K. El-Sawaf, Amal Abdel Fatah Nassar, El-Sayed El-Samanody. Synthesis, Magnetic, Spectral and Biological Studies of Copper(II) Complexes of 4-Benzoyl-3-Methyl-1-Phenyl-2-Pyrazolin-5-One N(4)-Substituted Thiosemicarbazones. Sci J Chem. 2014;2(3):17-26. doi: 10.11648/j.sjc.20140203.12

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@article{10.11648/j.sjc.20140203.12,
  author = {Ayman K. El-Sawaf and Amal Abdel Fatah Nassar and El-Sayed El-Samanody},
  title = {Synthesis, Magnetic, Spectral and Biological Studies of Copper(II) Complexes of 4-Benzoyl-3-Methyl-1-Phenyl-2-Pyrazolin-5-One N(4)-Substituted Thiosemicarbazones},
  journal = {Science Journal of Chemistry},
  volume = {2},
  number = {3},
  pages = {17-26},
  doi = {10.11648/j.sjc.20140203.12},
  url = {https://doi.org/10.11648/j.sjc.20140203.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjc.20140203.12},
  abstract = {The synthesis and characterization of copper(II) complexes with 4-benzoyl-3-methyl-1-phenyl-2-pyrazolin-5-one thiosemicarbazone and N(4)-substituted thiosemicarbazones are reported. Elemental analysis, molar conductivities, magnetic measurements and spectral (i.r., electronic, e.s.r., and n.m.r.) studies have been used to characterize the complexes. The i.r. spectra show that the thiosemicarbazones behave as bidentate ligands, either in the thione or thiolato form. Stereochemistries are proposed for the complexes on the basis of spectral and magnetic studies. Both the thiosemicarbazones and their complexes show either modest or no growth inhibitory activity against Aspergillus niger and Paecilomyces variotii.},
 year = {2014}
}

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TY  - JOUR
T1  - Synthesis, Magnetic, Spectral and Biological Studies of Copper(II) Complexes of 4-Benzoyl-3-Methyl-1-Phenyl-2-Pyrazolin-5-One N(4)-Substituted Thiosemicarbazones
AU  - Ayman K. El-Sawaf
AU  - Amal Abdel Fatah Nassar
AU  - El-Sayed El-Samanody
Y1  - 2014/08/30
PY  - 2014
N1  - https://doi.org/10.11648/j.sjc.20140203.12
DO  - 10.11648/j.sjc.20140203.12
T2  - Science Journal of Chemistry
JF  - Science Journal of Chemistry
JO  - Science Journal of Chemistry
SP  - 17
EP  - 26
PB  - Science Publishing Group
SN  - 2330-099X
UR  - https://doi.org/10.11648/j.sjc.20140203.12
AB  - The synthesis and characterization of copper(II) complexes with 4-benzoyl-3-methyl-1-phenyl-2-pyrazolin-5-one thiosemicarbazone and N(4)-substituted thiosemicarbazones are reported. Elemental analysis, molar conductivities, magnetic measurements and spectral (i.r., electronic, e.s.r., and n.m.r.) studies have been used to characterize the complexes. The i.r. spectra show that the thiosemicarbazones behave as bidentate ligands, either in the thione or thiolato form. Stereochemistries are proposed for the complexes on the basis of spectral and magnetic studies. Both the thiosemicarbazones and their complexes show either modest or no growth inhibitory activity against Aspergillus niger and Paecilomyces variotii.
VL  - 2
IS  - 3
ER  -

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