Elastic hard magnetic materials based resin-bond magnets with the determined space configuration of the magnetic field required for a three-dimensional cell growth which is essential for the tissue engineering have been produced. Technical tests of the samples as well as the theoretical study of the distribution of stray fields produced by ferromagnetic particles correspondingly distributed in the film have been carried out. In vitro еxperimental investigations of the gradient magnetic field influence on a cell differentiation on transplanted epithelial-like kidney cells culture of a pig embryo has been carried out. It has been shown that the adhesion, morphology and proliferation rate of the cells is determined not only by the magnetic field value but also by its gradient direction. It has been established that the cell adhesion efficiency is the highest when the magnetic field gradient is directed from the Petri dish bottom to the air-culture medium interface. The obtained results prove the possibility of an implementation of new gradient magnetic fields based methods in biotechnology and in particular in tissue engineering.
| Published in | American Journal of Bioscience and Bioengineering (Volume 2, Issue 6) |
| DOI | 10.11648/j.bio.20140206.11 |
| Page(s) | 72-77 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2015. Published by Science Publishing Group |
Resin-Bond Magnets, Cell Culture, Magnetic Field, Gradient Magnetic Field, Adhesion, Proliferation
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APA Style
Tamara A. Ignatyeva, Victor N. Voyevodin, Anatoly N. Goltsev, Victoria V. Kiroshka, Alexander M. Bovda, et al. (2015). Perspectives of Constant Gradient Magnetic Fields Applications in Biotechnology. American Journal of Bioscience and Bioengineering, 2(6), 72-77. https://doi.org/10.11648/j.bio.20140206.11
ACS Style
Tamara A. Ignatyeva; Victor N. Voyevodin; Anatoly N. Goltsev; Victoria V. Kiroshka; Alexander M. Bovda, et al. Perspectives of Constant Gradient Magnetic Fields Applications in Biotechnology. Am. J. BioSci. Bioeng. 2015, 2(6), 72-77. doi: 10.11648/j.bio.20140206.11
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Download@article{10.11648/j.bio.20140206.11,
author = {Tamara A. Ignatyeva and Victor N. Voyevodin and Anatoly N. Goltsev and Victoria V. Kiroshka and Alexander M. Bovda and Valery V. Kalynovskii and Alexey N. Velikodny and Peter A. Kutsenko and Vladimir Golub and Yuri Dzhedzheria and Irina Sharai},
title = {Perspectives of Constant Gradient Magnetic Fields Applications in Biotechnology},
journal = {American Journal of Bioscience and Bioengineering},
volume = {2},
number = {6},
pages = {72-77},
doi = {10.11648/j.bio.20140206.11},
url = {https://doi.org/10.11648/j.bio.20140206.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.bio.20140206.11},
abstract = {Elastic hard magnetic materials based resin-bond magnets with the determined space configuration of the magnetic field required for a three-dimensional cell growth which is essential for the tissue engineering have been produced. Technical tests of the samples as well as the theoretical study of the distribution of stray fields produced by ferromagnetic particles correspondingly distributed in the film have been carried out. In vitro еxperimental investigations of the gradient magnetic field influence on a cell differentiation on transplanted epithelial-like kidney cells culture of a pig embryo has been carried out. It has been shown that the adhesion, morphology and proliferation rate of the cells is determined not only by the magnetic field value but also by its gradient direction. It has been established that the cell adhesion efficiency is the highest when the magnetic field gradient is directed from the Petri dish bottom to the air-culture medium interface. The obtained results prove the possibility of an implementation of new gradient magnetic fields based methods in biotechnology and in particular in tissue engineering.},
year = {2015}
}
TY - JOUR T1 - Perspectives of Constant Gradient Magnetic Fields Applications in Biotechnology AU - Tamara A. Ignatyeva AU - Victor N. Voyevodin AU - Anatoly N. Goltsev AU - Victoria V. Kiroshka AU - Alexander M. Bovda AU - Valery V. Kalynovskii AU - Alexey N. Velikodny AU - Peter A. Kutsenko AU - Vladimir Golub AU - Yuri Dzhedzheria AU - Irina Sharai Y1 - 2015/01/14 PY - 2015 N1 - https://doi.org/10.11648/j.bio.20140206.11 DO - 10.11648/j.bio.20140206.11 T2 - American Journal of Bioscience and Bioengineering JF - American Journal of Bioscience and Bioengineering JO - American Journal of Bioscience and Bioengineering SP - 72 EP - 77 PB - Science Publishing Group SN - 2328-5893 UR - https://doi.org/10.11648/j.bio.20140206.11 AB - Elastic hard magnetic materials based resin-bond magnets with the determined space configuration of the magnetic field required for a three-dimensional cell growth which is essential for the tissue engineering have been produced. Technical tests of the samples as well as the theoretical study of the distribution of stray fields produced by ferromagnetic particles correspondingly distributed in the film have been carried out. In vitro еxperimental investigations of the gradient magnetic field influence on a cell differentiation on transplanted epithelial-like kidney cells culture of a pig embryo has been carried out. It has been shown that the adhesion, morphology and proliferation rate of the cells is determined not only by the magnetic field value but also by its gradient direction. It has been established that the cell adhesion efficiency is the highest when the magnetic field gradient is directed from the Petri dish bottom to the air-culture medium interface. The obtained results prove the possibility of an implementation of new gradient magnetic fields based methods in biotechnology and in particular in tissue engineering. VL - 2 IS - 6 ER -
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