Syzygium jambos (L.) Alstone belonging to the Myrtaceae family have been investigated for isolation of their secondary metabolites and evaluation of their biological activities. A total of three compounds have been isolated. The isolated compounds were identified by extensive analysis of their high resolution 1H-NMR spectroscopic data.The dried stem barks of Syzygium jambos was extracted with methanol. The concentrated methanolic extract was then partitioned with vacuum liquid chromatography. The first investigation was conducted with the VLC fraction-6 afforded one pentacyclic triterpenes (SJ-61), VLC fraction-9 afforded a sitosterol (SJ-92) and VLC fraction-16 afforded a triterpene 3-nor-2,3-fridelan derivative (SJ-184). In the brine shrimp lethality bioassay, The LC50 values were found to be 6.97, 18.07, 64.943, 247.596 and 12.75mg/ml for crude methanolic extract, carbon tetrachloride, chloroform and n-hexane soluble fractions of methanolic extract of Syzygium jambos respectively representing methanolic extract fraction as highly cytotoxic.
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American Journal of BioScience (Volume 3, Issue 2-1)
This article belongs to the Special Issue Pharmacological and Phytochemicals Investigation |
| DOI | 10.11648/j.ajbio.s.2015030201.13 |
| Page(s) | 12-18 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2015. Published by Science Publishing Group |
Medicinal Plant, Extraction, Isolation, Characterization, Cytotoxicity, Biological Activity
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APA Style
Majidul Haque, Mst. Marium Begum, Moynul Hasan, A. F. M. Towheedur Rahman, Md. Iftekhar Hussain, et al. (2015). Investigation of the Medicinal Potentials of Syzygium jambos (L.) Extract and Characterization of the Isolated Compounds. American Journal of BioScience, 3(2-1), 12-18. https://doi.org/10.11648/j.ajbio.s.2015030201.13
ACS Style
Majidul Haque; Mst. Marium Begum; Moynul Hasan; A. F. M. Towheedur Rahman; Md. Iftekhar Hussain, et al. Investigation of the Medicinal Potentials of Syzygium jambos (L.) Extract and Characterization of the Isolated Compounds. Am. J. BioScience 2015, 3(2-1), 12-18. doi: 10.11648/j.ajbio.s.2015030201.13
AMA Style
Majidul Haque, Mst. Marium Begum, Moynul Hasan, A. F. M. Towheedur Rahman, Md. Iftekhar Hussain, et al. Investigation of the Medicinal Potentials of Syzygium jambos (L.) Extract and Characterization of the Isolated Compounds. Am J BioScience. 2015;3(2-1):12-18. doi: 10.11648/j.ajbio.s.2015030201.13
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Download@article{10.11648/j.ajbio.s.2015030201.13,
author = {Majidul Haque and Mst. Marium Begum and Moynul Hasan and A. F. M. Towheedur Rahman and Md. Iftekhar Hussain and Mohammad Mizanur Rahman and Md. Hazrat Ali and Md. Ashraful Islam and Md. Zakir Sultan and Md. Reyad-ul- Ferdous and Choudhury Mahmood Hasan},
title = {Investigation of the Medicinal Potentials of Syzygium jambos (L.) Extract and Characterization of the Isolated Compounds},
journal = {American Journal of BioScience},
volume = {3},
number = {2-1},
pages = {12-18},
doi = {10.11648/j.ajbio.s.2015030201.13},
url = {https://doi.org/10.11648/j.ajbio.s.2015030201.13},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbio.s.2015030201.13},
abstract = {Syzygium jambos (L.) Alstone belonging to the Myrtaceae family have been investigated for isolation of their secondary metabolites and evaluation of their biological activities. A total of three compounds have been isolated. The isolated compounds were identified by extensive analysis of their high resolution 1H-NMR spectroscopic data.The dried stem barks of Syzygium jambos was extracted with methanol. The concentrated methanolic extract was then partitioned with vacuum liquid chromatography. The first investigation was conducted with the VLC fraction-6 afforded one pentacyclic triterpenes (SJ-61), VLC fraction-9 afforded a sitosterol (SJ-92) and VLC fraction-16 afforded a triterpene 3-nor-2,3-fridelan derivative (SJ-184). In the brine shrimp lethality bioassay, The LC50 values were found to be 6.97, 18.07, 64.943, 247.596 and 12.75mg/ml for crude methanolic extract, carbon tetrachloride, chloroform and n-hexane soluble fractions of methanolic extract of Syzygium jambos respectively representing methanolic extract fraction as highly cytotoxic.},
year = {2015}
}
TY - JOUR T1 - Investigation of the Medicinal Potentials of Syzygium jambos (L.) Extract and Characterization of the Isolated Compounds AU - Majidul Haque AU - Mst. Marium Begum AU - Moynul Hasan AU - A. F. M. Towheedur Rahman AU - Md. Iftekhar Hussain AU - Mohammad Mizanur Rahman AU - Md. Hazrat Ali AU - Md. Ashraful Islam AU - Md. Zakir Sultan AU - Md. Reyad-ul- Ferdous AU - Choudhury Mahmood Hasan Y1 - 2015/02/27 PY - 2015 N1 - https://doi.org/10.11648/j.ajbio.s.2015030201.13 DO - 10.11648/j.ajbio.s.2015030201.13 T2 - American Journal of BioScience JF - American Journal of BioScience JO - American Journal of BioScience SP - 12 EP - 18 PB - Science Publishing Group SN - 2330-0167 UR - https://doi.org/10.11648/j.ajbio.s.2015030201.13 AB - Syzygium jambos (L.) Alstone belonging to the Myrtaceae family have been investigated for isolation of their secondary metabolites and evaluation of their biological activities. A total of three compounds have been isolated. The isolated compounds were identified by extensive analysis of their high resolution 1H-NMR spectroscopic data.The dried stem barks of Syzygium jambos was extracted with methanol. The concentrated methanolic extract was then partitioned with vacuum liquid chromatography. The first investigation was conducted with the VLC fraction-6 afforded one pentacyclic triterpenes (SJ-61), VLC fraction-9 afforded a sitosterol (SJ-92) and VLC fraction-16 afforded a triterpene 3-nor-2,3-fridelan derivative (SJ-184). In the brine shrimp lethality bioassay, The LC50 values were found to be 6.97, 18.07, 64.943, 247.596 and 12.75mg/ml for crude methanolic extract, carbon tetrachloride, chloroform and n-hexane soluble fractions of methanolic extract of Syzygium jambos respectively representing methanolic extract fraction as highly cytotoxic. VL - 3 IS - 2-1 ER -
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