Hyperparathyroidism is a common endocrinopathy, and parathyroid scintigraphy is part of the preoperative work-up. A prerequisite for adenoma surgery is precise localization of the pathological gland(s) concerned. Our aim was to review the parathyroid scans performed for hyperparathyroidism in Senegal. We carried out a retrospective study over a period of 2.5 years, including patients with hyperparathyroidism who underwent parathyroid scintigraphy with 99mTc-MIBI, in the nuclear medicine department of the Idrissa Pouye General Hospital in Dakar. A total of 66 patients were included. The mean age was 52 years, with a sex ratio (M/F) of 0.34. The majority of patients were from the capital, Dakar (93%). Primary hyperparathyroidism was the predominant indication (70%). Most patients were symptomatic. Mean parathyroid hormone (PTH) and Calcemia were 464 pg/ml and 98 mg/l respectively. Ultrasound revealed a thyroid nodule in 35% of cases. The scintigraphy was in favour of parathyroid adenoma (30%) with a predominant right upper location (right P4) (35%) and poor concordance between cervical ultrasound and parathyroid scintigraphy was observed with a kappa coefficient k=0.04. Parathyroid scintigraphy with 99mTc-MIBI allows precise localization of hyper functioning glands, enabling unilateral or minimally invasive cervical surgery to be adopted and reducing the therapeutic failure rate.
| Published in | European Journal of Biophysics (Volume 12, Issue 1) |
| DOI | 10.11648/ejb.20241201.12 |
| Page(s) | 6-14 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Hyperparathyroidism, Scintigraphy, 99mTc-MIBI, Senegal
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APA Style
Bathily, E. H. A. L., Thiaw, G., Diop, O., Djigo, M. S., Gueye, K., et al. (2024). 99mTc-Mibi Parathyroid Scintigraphy in the Exploration of Hyperparathyroidism in Senegal: A Study of 66 Cases in the Idrissa Pouye General Hospital, Dakar. European Journal of Biophysics, 12(1), 6-14. https://doi.org/10.11648/ejb.20241201.12
ACS Style
Bathily, E. H. A. L.; Thiaw, G.; Diop, O.; Djigo, M. S.; Gueye, K., et al. 99mTc-Mibi Parathyroid Scintigraphy in the Exploration of Hyperparathyroidism in Senegal: A Study of 66 Cases in the Idrissa Pouye General Hospital, Dakar. Eur. J. Biophys. 2024, 12(1), 6-14. doi: 10.11648/ejb.20241201.12
AMA Style
Bathily EHAL, Thiaw G, Diop O, Djigo MS, Gueye K, et al. 99mTc-Mibi Parathyroid Scintigraphy in the Exploration of Hyperparathyroidism in Senegal: A Study of 66 Cases in the Idrissa Pouye General Hospital, Dakar. Eur J Biophys. 2024;12(1):6-14. doi: 10.11648/ejb.20241201.12
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Download@article{10.11648/ejb.20241201.12,
author = {El Hadji Amadou Lamine Bathily and Gora Thiaw and Ousseynou Diop and Mamoudou Salif Djigo and Kalidou Gueye and Dioudé Diaw and Olatounde Herbert Fachinan and Mohamed Chekhma and Boucar Ndong and Omar Ndoye and Mamadou Mbodj},
title = {99mTc-Mibi Parathyroid Scintigraphy in the Exploration of Hyperparathyroidism in Senegal: A Study of 66 Cases in the Idrissa Pouye General Hospital, Dakar},
journal = {European Journal of Biophysics},
volume = {12},
number = {1},
pages = {6-14},
doi = {10.11648/ejb.20241201.12},
url = {https://doi.org/10.11648/ejb.20241201.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.ejb.20241201.12},
abstract = {Hyperparathyroidism is a common endocrinopathy, and parathyroid scintigraphy is part of the preoperative work-up. A prerequisite for adenoma surgery is precise localization of the pathological gland(s) concerned. Our aim was to review the parathyroid scans performed for hyperparathyroidism in Senegal. We carried out a retrospective study over a period of 2.5 years, including patients with hyperparathyroidism who underwent parathyroid scintigraphy with 99mTc-MIBI, in the nuclear medicine department of the Idrissa Pouye General Hospital in Dakar. A total of 66 patients were included. The mean age was 52 years, with a sex ratio (M/F) of 0.34. The majority of patients were from the capital, Dakar (93%). Primary hyperparathyroidism was the predominant indication (70%). Most patients were symptomatic. Mean parathyroid hormone (PTH) and Calcemia were 464 pg/ml and 98 mg/l respectively. Ultrasound revealed a thyroid nodule in 35% of cases. The scintigraphy was in favour of parathyroid adenoma (30%) with a predominant right upper location (right P4) (35%) and poor concordance between cervical ultrasound and parathyroid scintigraphy was observed with a kappa coefficient k=0.04. Parathyroid scintigraphy with 99mTc-MIBI allows precise localization of hyper functioning glands, enabling unilateral or minimally invasive cervical surgery to be adopted and reducing the therapeutic failure rate.
},
year = {2024}
}
TY - JOUR T1 - 99mTc-Mibi Parathyroid Scintigraphy in the Exploration of Hyperparathyroidism in Senegal: A Study of 66 Cases in the Idrissa Pouye General Hospital, Dakar AU - El Hadji Amadou Lamine Bathily AU - Gora Thiaw AU - Ousseynou Diop AU - Mamoudou Salif Djigo AU - Kalidou Gueye AU - Dioudé Diaw AU - Olatounde Herbert Fachinan AU - Mohamed Chekhma AU - Boucar Ndong AU - Omar Ndoye AU - Mamadou Mbodj Y1 - 2024/02/05 PY - 2024 N1 - https://doi.org/10.11648/ejb.20241201.12 DO - 10.11648/ejb.20241201.12 T2 - European Journal of Biophysics JF - European Journal of Biophysics JO - European Journal of Biophysics SP - 6 EP - 14 PB - Science Publishing Group SN - 2329-1737 UR - https://doi.org/10.11648/ejb.20241201.12 AB - Hyperparathyroidism is a common endocrinopathy, and parathyroid scintigraphy is part of the preoperative work-up. A prerequisite for adenoma surgery is precise localization of the pathological gland(s) concerned. Our aim was to review the parathyroid scans performed for hyperparathyroidism in Senegal. We carried out a retrospective study over a period of 2.5 years, including patients with hyperparathyroidism who underwent parathyroid scintigraphy with 99mTc-MIBI, in the nuclear medicine department of the Idrissa Pouye General Hospital in Dakar. A total of 66 patients were included. The mean age was 52 years, with a sex ratio (M/F) of 0.34. The majority of patients were from the capital, Dakar (93%). Primary hyperparathyroidism was the predominant indication (70%). Most patients were symptomatic. Mean parathyroid hormone (PTH) and Calcemia were 464 pg/ml and 98 mg/l respectively. Ultrasound revealed a thyroid nodule in 35% of cases. The scintigraphy was in favour of parathyroid adenoma (30%) with a predominant right upper location (right P4) (35%) and poor concordance between cervical ultrasound and parathyroid scintigraphy was observed with a kappa coefficient k=0.04. Parathyroid scintigraphy with 99mTc-MIBI allows precise localization of hyper functioning glands, enabling unilateral or minimally invasive cervical surgery to be adopted and reducing the therapeutic failure rate. VL - 12 IS - 1 ER -
Nuclear Medicine Department, Idrissa Pouye General Hospital (HOGIP), Dakar, Senegal; Biophysical Laboratory, Faculty of Medicine, Pharmacy and Odontology (FMPO), Cheikh Anta Diop University (UCAD), Dakar, Senegal
